Treatment of Small Stomach GISTs
Some stomach GISTs smaller than 2 cm may pose more risk than previously thought according to a new report from China.
ASCO features many updates on GIST trials
ASCO features many updates on GIST trials. Promising results for the immunotherapy approach to treating cancer dominated the annual conference of the ASCO and represent one of the biggest developments in cancer research since the advent [...]
DOG1 Gene and GIST – What is the Relationship?
Jonathan Fletcher and Sebastian Bauer of the LRG’s Research Team were among the authors in a study to be published in Cancer Research that examined the relationship between GIST and the expression of the gene DOG1.
Research Team Meets in New Jersey
The LRG research team meets four times a year, with at least one in-person meeting per year. This year, the team held its in-person meeting at the LRG office in New Jersey March 22-24, 2013.
Join Our Tissue Bank – Help the LRG Find A Cure
Join our Tissue Bank - Help the LRG in the search for a cure. Wildtype GIST tissue is needed for a current LRG Research Team project. If you or a loved one are a wildtype GIST patient, please help the LRG Research Team in its search for the cure by donating your tissue.
First report of a GIST patient responding to a BRAF inhibitor
First report of a GIST patient responding to a BRAF inhibitor. Dr. Gerald Falchook and colleagues at MD Anderson Cancer Center provided the first report of a GIST patient responding to a BRAF inhibitor. The BRAF gene is frequently mutated in melanoma and BRAF inhibitors provide one of the most important therapies available for melanoma patients
Treatment Guidelines for GIST
Treatment guidelines for GIST are established by experts to ensure that patients receive adequate care and appropriate therapies.
Imatinib Plasma Levels Revisited – An editorial post by Jerry Call
Since we have gotten a number of questions about Gleevec (imatinib) plasma levels and testing, I think it’s time to revisit the subject, especially for newer members. Since this is a very complex subject, this may take a few emails and a few days.
Sutent Treatment Use Trial Results
Patients with GIST who received sunitinib using a flexible dose approach to manage adverse events remained on treatment longer than those who received the strict dose/schedule and exhibited better clinical outcomes (longer time to tumor progression and longer overall survival).
Anemia has multiple causes and treatments
When your blood doesn't have enough healthy red blood cells or have enough hemoglobin, you can tire quickly or feel weak. This condition is called anemia. The fatigue that comes with anemia can lead to a decreased quality of life. Some fatigue is not related to anemia. Anemia has three broad causes; blood loss, decreased blood cell production and increased blood cell destruction. The first two are the most relevant for GIST patients.