The Life Raft Group is pleased to announce the release of the seventh issue of The GIST Cancer Journal, the official journal of the Life Raft Group and the first academic journal devoted solely to GIST. The journal is intended to serve as a comprehensive and authoritative resource of scientifically valid information for physicians and allied health care professionals regarding advances in the diagnosis and treatment of GIST. Editorial content focuses on the impact of translational research in oncology and gastroenterology relating specifically to GIST. As the official medical journal of the Life Raft Group, it also provides a forum for GIST patient advocacy. It is published quarterly.

In this issue of the GIST Cancer Journal

The GIST Cancer Journal

Articles in this month’s journal highlight key issues in optimizing the diagnosis and treatment of GIST: identifying drug sensitivities with mutational analysis,  the role of the gastroenterologist in diagnosing GIST, biomarker analysis, and surgical intervention after neoadjuvant therapy.

Dr. Jonathan Trent, editor of the GIST Cancer Journal, discusses in his editor’s memo the tools available for making the diagnosis of gastrointestinal stromal tumor (GIST) and how the components in this journal can be one of these tools.

One of the articles, Identifying Drug Sensitivities of GIST With Mutational Analysis to Optimize Treatment Approaches by Sandeep K. Reddy, MD and Rebecca Feldman, PhD, discusses major strides in biomarker analysis in gastrointestinal stromal tumors (GIST) that could open new avenues of treatment beyond conventional approaches.

Interview – Insights on Tumor Profiling: Finding the Elusive but Pivotal Piece of the GIST Puzzle With Patterns of Biomarker Expression features comments by Sandeep K. Reddy, MD, the Chief Medical Officer at Caris Life Sciences, and Rebecca Feldman, PhD, a Research Scientist and Molecular Science Liaison.

Once GIST is diagnosed, the first clinician to meet the challenge is likely to be a gastroenterologist. Read this report, The Gastroenterologist and GIST: A Vital Member of the Team Becomes More of a ‘Diagnostician’ in the Continuum of Care about options available and how they can be used in daily practice by David H. Kerman, MD and Afonso C. Ribeiro, MD.

A patient case report outlines the value of surgical management of GIST: Case report: RO Resection of Large GIST After Neoadjuvant Therapy with Imatinib by Nicholai Stephens, MD, Philip Leggett, MD, Luis Escola-Rodriguez, MD, Pierre Khoury, MD and David Gochnour, MD.

GIST Cancer Journal October